New Cell Lines tools in Genevestigator

Genevestigator is a gene-expression analysis tool to which scientists at VIB have free access. Recently, Genevestigator has launched a new module in their software, called the 'Cell Lines tool'.

Cell Lines tool

Two new tools for the analysis across cell lines have just been released in Genevestigator

  • Find cell lines strongly expressing your genes of interest (CONDITION SEARCH) or

  • Find genes specifically expressed in chosen cell lines (GENE SEARCH)

Both tools are integrated seamlessly with all other functions in Genevestigator and use the same advanced visualizations.

For Human, over 500 different categories of cell lines were curated and are available in the tools.

Two types of cell lines are represented: neoplastic and non-neoplastic.

  • The neoplastic cell lines are structured based on the cancer type of origin,
  • whereas non-neoplastic cell lines include embryonic, immortalized, induced pluripotent stem cells and other types of cell lines. 

Screenshot of the Cell Lines tool in the CONDITION SEARCH toolset. Legend: View average gene expression across different types of cell lines (upper section) and explore the details of each cell line on the level of individual samples (lower section).

 

New curated content added to Genevestigator

 During the past months, a significant amount of new experiments was manually curated. Well described and quality controlled experiments were added in the following areas:

  • Cardiology: CAD, MI, IBS
  • Nephrology and urology: chronic kidney diseases
  • Endocrinology: Diabetes and related diseases, insulin resistance, obesity, polycystic ovary syndrom
  • Diseases of the gastrointestinal tract (IBD, celiac disease, H. pylori, chronic intestinal inflammation)
  • Pneumology: IPF, PAH, NSCLC
  • Dermatology: Psoriasis, atopic dermatitis, skin cancer, hair follicle, leprosy, Sotos Syndrome
  • Toxicology
  • Various blood datasets
  • NIH stem cell database

If you haven't used GENEVESTIGATOR for a while, it is worth a look.

Best regards, 

The GENEVESTIGATOR Team


To access Genevestigator at VIB, please check our Genevestigator page.