IPA summer release 2016

Published Date: August 04th, 2016: IPA┬« is a powerful web-based knowledge base system designed for biologists.

Read the full release notes (here).

'BioProfiler' and 'Advanced Analytics' news are not relevant for us as our license does not include these tools

We reproduce below the part about content updates for the IPA core modules

Other Application Improvements

Enhanced Analyses, Datasets & Lists Overlay

Bar charts now appear by default on the network or pathway when selecting rows in the Matching Molecules table. Make publication-ready graphics by repositioning bar charts anywhere on a network or pathway by dragging the chart with your mouse.

Select and add multiple items from the IPA project manager at one time to overlay.

Filter by Symbol or by Display name in the Matching Molecules table.

Option to export the image of only the rows you select from the Matching Molecules table.

Content Updates

  • ~85,0000 new findings (bringing total to over 5.5 million findings), including:
  • ~39,000 new Expert findings
  • ~600 new ExpertAssist findings
  • ~46,000 new protein-protein interactions from the BioGRID database
  • ~12,000 new cancer mutation-to-disease association findings from COSMIC
  • ~3700 new mutation-to-disease findings from ClinVar
  • ~1200 new disease-to-drug findings from ClinicalTrials.gov
  • ~900 new disease-to-target findings from ClinicalTrials.gov
  • ~800 new gene-to-biological process assertions from Gene Ontology (GO)
  • ~1100 new mouse knockout-to-phenotype findings in Mouse Genome Database (JAX Labs)
  • ~900 new protein-protein interactions from the IntAct database
  • ~300 new biomarker findings from GVK Biosciences
  • 100 gene-to-disease findings from OMIM

Note: Protein-protein interactions from the MINT database are now part of the IntAct database in IPA.

Two new Canonical Pathways

  • Inflammasome pathway
  • Cancer Drug Resistance By Drug Efflux

To access IPA at VIB, please check our IPA page

To update IPA core analyses to the new content, read our IPA-FAQ page (VIB users only).